Mercedes-Benz S-Class, W221 / V221 (EU)

Coolant capacity & service interval

Mercedes-Benz S-Class, W221 / V221 (EU) coolant capacity ranges from 1,5 to 11,8 liters. Service intervals include 36 months or 250000 km / 180 months. The data covers 55 configurations.

The configuration chart below lists fill volumes and service intervals for each engine and trim variant.

TypeSpecifications
S 250 CDI, 221.003/103 (2011-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 350 BlueTEC, 221.026/126 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 350 BlueTEC 4MATIC, 221.083/183 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 350 CGI 4MATIC BlueEFFICIENCY, 221.082/182 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 350 CGI BlueEFFICIENCY, 221.057/157 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 500 4MATIC BlueEFFICIENCY, 221.094/194 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 500 BlueEFFICIENCY / S 550 CGI, 221.073/173 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 550 4MATIC CGI, 221.094/194 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 63 AMG (400 KW), 221.074/174 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 63 AMG (420 KW), 221.074/174 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 65 AMG, 221.179 (2010-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 350, 221.056/156 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 350 CDI 4MATIC BlueEFFICIENCY, 221.080/180 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 350 CDI BlueEFFICIENCY, 221.022/122 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 400 HYBRID, 221.095/195 (2009-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 450, 221.070/170 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 450 4MATIC, 221.084/184 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 450 CDI, 221.028/128 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 450 CDI L Guard, 221.128 Z07 (2009-2013)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 500 / S 550, 221.071/171 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 500 4MATIC / S 550 4MATIC, 221.086/186 (2009-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 600, 221.176 (2009-2013)
  • Use: Normal
  • Between min and max.
  • Change 36 months
S 600 Pullman Guard, 221.176 Z19 (2009-2013)
  • Use: Normal
  • Between min and max.
  • Change 36 months
S 350 4MATIC, 221.087/187 (2008-2010)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 63 AMG, 221.077/177 (2008-2010)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 280, 221.054/154 (2007-2009)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 300, 221.054/154 (2007-2009)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 320 CDI, 221.022/122 (2007-2009)
  • Use: Normal
  • Capacity 7,5 liter
  • Change 250000 km/ 180 months
S 320 CDI 4MATIC, 221.080/180 (2007-2009)
  • Use: Normal
  • Capacity 7,5 liter
  • Change 250000 km/ 180 months
S 320 CDI 4MATIC DPF, 221.080/180 (2007-2009)
  • Use: Normal
  • Capacity 7,5 liter
  • Change 250000 km/ 180 months
S 320 CDI DPF, 221.022/122 (2007-2009)
  • Use: Normal
  • Capacity 7,5 liter
  • Change 250000 km/ 180 months
S 350, 221.056/156 (2007-2009)
  • Use: Normal
  • Capacity 8 liter
  • Change 250000 km/ 180 months
S 420 CDI, 221.028/128 (2007-2009)
  • Use: Normal
  • Capacity 9 liter
  • Change 250000 km/ 180 months
S 420 CDI DPF, 221.028/128 (2007-2009)
  • Use: Normal
  • Capacity 9 liter
  • Change 250000 km/ 180 months
S 450, 221.070/170 (2007-2009)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 450 4MATIC, 221.084/184 (2007-2009)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 500 / S 550, 221.071/171 (2007-2009)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 500 4MATIC / S 550 4MATIC, 221.086/186 (2007-2009)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 600, 221.176 (2007-2009)
  • Use: Normal
  • Capacity 8,8 liter
  • Change 250000 km/ 180 months
  • S 600, 221.176 (2007-2009)
  • Intercooler
  • Use: Normal
  • Capacity 1,5 liter
  • Change 36 months
S 65 AMG, 221.179 (2007-2010)
  • Use: Normal
  • Capacity 11,8 liter
  • Change 250000 km/ 180 months
  • S 65 AMG, 221.179 (2007-2010)
  • Intercooler
  • Use: Normal
  • Capacity 2,1 liter
  • Change 36 months
S 320 CDI 4MATIC DPF, 221.080/180 (2006-2007)
  • Use: Normal
  • Capacity 7,5 liter
  • Change 250000 km/ 180 months
S 420 CDI DPF, 221.028/128 (2006-2007)
  • Use: Normal
  • Capacity 9 liter
  • Change 250000 km/ 180 months
S 450, 221.070/170 (2006-2007)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 450 4MATIC, 221.084/184 (2006-2007)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 500 4MATIC, 221.086/186 (2006-2007)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 63 AMG, 221.077/177 (2006-2008)
  • Use: Normal
  • Between min and max.
  • Change 250000 km/ 180 months
S 65 AMG, 221.179 (2006-2007)
  • Use: Normal
  • Capacity 11,8 liter
  • Change 250000 km/ 180 months
  • S 65 AMG, 221.179 (2006-2007)
  • Intercooler
  • Use: Normal
  • Capacity 2,1 liter
  • Change 36 months
S 320 CDI DPF, 221.022/122 (2005-2007)
  • Use: Normal
  • Capacity 7,5 liter
  • Change 250000 km/ 180 months
S 350, 221.056/156 (2005-2007)
  • Use: Normal
  • Capacity 8 liter
  • Change 250000 km/ 180 months
S 500, 221.071/171 (2005-2007)
  • Use: Normal
  • Capacity 8,5 liter
  • Change 250000 km/ 180 months
S 600, 221.176 (2005-2007)
  • Use: Normal
  • Capacity 8,8 liter
  • Change 250000 km/ 180 months
  • S 600, 221.176 (2005-2007)
  • Intercooler
  • Use: Normal
  • Capacity 1,5 liter
  • Change 36 months

Other Systems