Mercedes-Benz E-Class, W214 / V214 / S214 (USA / CAN)

Additional Notes

• The Mercedes-Benz E-Class W214/V214/S214 E 350 variants carry a split cooling architecture, with a primary system holding 14 liters and a separate secondary system holding 3 liters, bringing the combined total to 17 liters across both circuits.
• The E 450 4MATIC lists a single cooling system with an 18-liter capacity, the largest single-circuit figure among the configurations covered in these specifications.
• The E 53 Hybrid AMG 4MATIC mirrors the dual-circuit layout seen in the E 350 variants, pairing an 18-liter primary system with a 3-liter secondary system, for a combined total of 21 liters across both circuits.
• The secondary cooling circuit, rated at 3 liters, appears across the E 350, E 350 4MATIC, and E 53 Hybrid AMG 4MATIC configurations, while the E 450 4MATIC has no secondary circuit listed in its specifications.
• All configurations share an identical service interval of 124,000 miles or 120 months under normal use conditions, meaning the time-based limit reaches 10 years regardless of mileage accumulation.
• The 120-month time limit means coolant replacement is due at a decade of service even when the 124,000-mile threshold has not been reached, whichever condition occurs first.
• The E 350 and E 350 4MATIC share identical primary and secondary capacities of 14 liters and 3 liters respectively, indicating the addition of the 4MATIC all-wheel-drive system does not alter the cooling system volume in these specifications.
• The E 53 Hybrid AMG 4MATIC primary system capacity of 18 liters matches the single-circuit figure of the E 450 4MATIC, despite the E 53 carrying an additional 3-liter secondary circuit on top of that volume.